Psilocybin Therapy in Oregon
Psilocybin Therapy in Oregon: How Legal Access Works
Who can take part, what a session involves, what the research shows, and how to start.
Psilocybin therapy is legal in Oregon for adults 21 and over, through supervised sessions with a state-licensed facilitator at a licensed service center. Oregon was the first US state to allow it. No diagnosis, prescription, or Oregon residency is required, and every session includes a preparation session before and integration support after.
From Ayeterra’s Oregon-licensed facilitators, sourced to the statute, the rules, and the primary research. Last updated September 15, 2026.
Is psilocybin therapy legal in Oregon?
Yes, inside the state’s licensed program. In November 2020 Oregon voters passed Measure 109, the Oregon Psilocybin Services Act, now written into Oregon law as ORS 475A. The Oregon Health Authority spent two years writing the rules, and the first licensed service center opened in 2023. Since then thousands of adults each year have done what most people call psilocybin therapy or Oregon psychedelic therapy, under the state’s rules.
What the law allows:
- Adults 21 and over may buy and consume psilocybin at a licensed service center, during a supervised administration session, with a licensed facilitator present (ORS 475A.498).
- Four kinds of licenses make the system work: manufacturers who grow it, labs that test it, service centers that host sessions, and facilitators who guide them.
- The actual mushroom, and only one species: Psilocybe cubensis, grown in Oregon by licensed producers and lab-tested. Synthetic psilocybin is not permitted.
- No diagnosis, prescription, or referral is needed. Oregon’s model is supported adult use, not medical treatment.
Measure 109 is not Measure 110. Measure 110 (also 2020) reduced criminal penalties for possessing small amounts of drugs; the legislature rolled most of that back in 2024 (House Bill 4002). Neither measure made it legal to buy, carry, or take psilocybin outside a licensed session. The legal path is a service center, a licensed facilitator, and nothing leaves the building.
Who can take part in Oregon’s psilocybin program?
Most healthy adults are eligible. Everyone is screened, and screening is where honest fit gets decided.
You can take part if you are
- 21 or older, with valid ID
- Able to complete a preparation session with a licensed facilitator and a standardized client information form
- In Oregon for the session itself; there is no residency requirement, and many people travel in
- Willing to arrange a ride home; you cannot drive yourself after a session
Screening will pause or decline if you
- Have taken lithium in the last 30 days
- Have ever been diagnosed with active psychosis
- Are currently having thoughts of harming yourself or others
- Answer other questions on the form that call for extra support, such as a client support person present during your session
Some things are not exclusions but deserve a conversation first, including certain medications, heart conditions, and pregnancy. Disclose everything at screening. A facilitator who tells you “not yet” or “talk to your doctor first” is doing the job well, and Ayeterra’s will.
How does psilocybin therapy work in Oregon, step by step?
Five stages. The middle three are required by Oregon rule; the first and last are where a good facilitator earns the fee.
Consultation to integration
- A free consultation and screening under Oregon’s rules, with a straight read on fit
- Preparation with your facilitator, more than the one session Oregon requires
- The session at a licensed service center, your facilitator present the whole time
- A check-in within 72 hours and integration support, included
Every step, hour by hour, is on How It Works.
See how it works, step by step →Start with the conversation
Free, confidential, no commitment. Fifteen minutes to ask your questions and find out whether this is a fit, and when.
Book a free consultation Or call 503-713-5644 · Adults 21+Not sure whether something in your history is a problem? That is a consultation question, and it is free to ask. The full criteria, medication notes, and Oregon’s safety data are on the safety and screening page.
Ask on a free consultationWhat happens during a psilocybin session?
A session is quieter than most people expect. Eyeshades, music, a comfortable place to lie down, and a licensed facilitator who is there for you and not on their phone.
The setting
- A private room for one-on-one sessions, or a shared space with a facilitator ratio set by rule for groups
- You buy the psilocybin at the center and take it there; it cannot leave the premises
- No touch beyond what you have agreed to in writing beforehand
- Supportive touch and a support person are options, never defaults
Your facilitator
- Completed a state-approved training program, passed the state exam and a background check
- Present from the moment you take the dose until the session ends
- Keeps you safe and lets the experience be yours; Oregon’s rules keep facilitators from directing or interpreting it for you
- Follows up within 72 hours and offers integration
How long a session lasts is set by Oregon rule and depends on the dose (OAR 333-333-5250). These are minimums; most people stay longer.
| Dose (psilocybin analyte) | Minimum session length | Ayeterra format |
|---|---|---|
| Under 5 mg | 1 hour | Low-dose group |
| 5 to under 10 mg | 2 hours | Private low-dose introduction |
| 10 to under 25 mg | 4 hours | Lighter one-on-one; first session of a two-session program |
| 25 to 35 mg | 5 hours | Group session; standard one-on-one |
| 35 to 50 mg | 6 hours | Upper-range one-on-one, set case by case |
What does the research say about psilocybin therapy?
Psilocybin has been studied seriously for more than a decade, mostly for depression, anxiety, and distress in people facing serious illness. The results are real, and they are not magic. Here is what the strongest trials found.
All from peer-reviewed journals. Trial participants were screened and supported before, during, and after, which is also how Oregon’s program is structured.
- Johns Hopkins, JAMA Psychiatry (2021). Two psilocybin sessions with supportive therapy in adults with major depression. At four weeks, 71 percent had responded and 54 percent were in remission, with large, rapid reductions in depression scores.
- Imperial College London, New England Journal of Medicine (2021). Psilocybin compared head-to-head with a six-week course of escitalopram. Both groups improved; the difference on the main depression measure was not statistically significant. Read that as “comparable,” not “better.”
- Johns Hopkins and NYU (2016). A single high-dose session for anxiety and depression in people with life-threatening cancer. Most participants showed clinically significant reductions that held at six months. This remains the strongest evidence base of all.
- Newer and smaller: early trials in PTSD, alcohol use, and anorexia are promising and still early. It is fair to be curious and to keep expectations honest.
Safety in the real program. Oregon now publishes service center data. In the first quarter of 2025, 1,509 clients received services and six behavioral, medical, or post-session reactions were reported to the state (Oregon Health Authority, June 2025). Psilocybin has low physical toxicity; the real risks are psychological, and screening, setting, and a trained facilitator exist to manage them.
Oregon’s program is not medical treatment, and a session is not a substitute for care you are already getting. No facilitator can promise you an outcome. What a good one can promise is preparation, a safe setting, and someone beside you the whole way.
What does psilocybin therapy cost in Oregon?
Between $75 for a low-dose group session and about $2,100 to $2,300 all-in for a private one-on-one, with retreats from $3,000. With Ayeterra every price is published, including what the psilocybin itself costs, and every price includes preparation beyond Oregon’s one required session, the session room, and integration. Insurance does not cover psilocybin services in Oregon.
Price should never be the reason someone does not have a session. Sliding-scale access is real and handled on the consultation, with no forms and no proof of hardship.
Every price includes preparation beyond Oregon’s one required session, the session room, and integration support.
See every price and what it includes →How does Ayeterra work?
Ayeterra is a team of facilitators licensed by the State of Oregon, working at licensed service centers in Portland and Ashland. You work with one facilitator from preparation through integration, and the whole team holds to the same standard for how much preparation a person gets and what integration support looks like.
A licensed team, not one person
- Every facilitator licensed by the State of Oregon and trained in a state-approved program
- Backgrounds in nursing, social work, and other professions, brought as depth, not as clinical services
- You are matched with a facilitator, not assigned to whoever is free (meet the team)
More preparation than the state requires
- Oregon requires one preparation session; ours go beyond it
- Individualized, not a script: what works for you, and tools you keep afterward
- Readiness is most of what makes a session go well
Integration built in
- Preparation, the session, and integration treated as one arc
- Integration support is in every price, not an add-on
- With your consent, we coordinate with a therapist you already see (details for therapists)
Honest fit, published prices
- We tell you plainly if this is not right for you, or not yet (how screening works)
- Every price is on the site, including the psilocybin
- Sliding-scale access on the consultation, no forms, no proof of hardship
Choose the format that fits:
One-on-one session
- Your own licensed facilitator, start to finish
- Dose of 20 to 50 mg set together in preparation
Group session
- Capped at eight, usually six
- Your own experience, with connection built in around it
Low-dose introduction
- A gentle dose, a real session
- The lowest-commitment way to find out what this is like
Multi-day retreat
- Three or five nights, lodging and meals included
- Four to six people
Questions people ask before their first session
Is psilocybin therapy in Oregon actual therapy?
“Psilocybin therapy” or “psychedelic therapy” is what most people call it, and it is the term the field uses. Legally, Oregon’s program is supervised adult use with a licensed facilitator, not medical or mental health treatment, and facilitators do not diagnose or treat conditions. Many people do this work alongside a therapist, and with your consent Ayeterra can coordinate with yours.
Do I need a diagnosis or a doctor’s referral?
No. Any adult 21 or over can begin with a consultation. Screening looks at safety, not at whether you qualify for a diagnosis.
Do I have to live in Oregon?
No. There is no residency requirement, and a large share of clients travel in from other states. You need to be in Oregon for the session itself. Ayeterra does not provide psilocybin services anywhere else.
How long does the whole process take?
Consultation to session commonly runs two to six weeks, set by screening and genuine readiness rather than by the calendar. People traveling from out of state often fold preparation into a planned trip.
Can I bring someone with me?
Sometimes, and sometimes you must. Oregon allows a client support person to be present, and answers on the screening form can make one required. Talk it through with your facilitator during preparation.
What kind of psilocybin is used, and how much?
Real mushrooms, not a synthetic compound: only Psilocybe cubensis grown by Oregon-licensed producers and lab-tested for potency and contaminants, taken as whole dried mushroom, ground mushroom, extract, or an edible. Doses run from under 5 mg for low-dose sessions up to Oregon’s 50 mg cap, chosen with your facilitator in preparation.
Where are the mushrooms grown, and are they tested?
It is the actual mushroom, nothing synthetic. Oregon’s program allows only Psilocybe cubensis, grown in Oregon by Oregon-licensed manufacturers on premises the state inspects. Lab-made psilocybin and wild-harvested mushrooms are both prohibited. Every batch is tested by an Oregon-licensed lab for potency and contaminants before it can be sold, then tracked in the state’s product tracking system from grow to service center. The only place you can buy it is the licensed service center where your session happens, and only during that session.
Where can I do psilocybin therapy near me in Oregon?
Only at a licensed service center, and Oregon has about two dozen of them, concentrated in Portland, the Willamette Valley, Bend, and Ashland. Ayeterra’s facilitators work at licensed service centers in Portland and Ashland, and the consultation is the same wherever you are. If you are coming from out of state, most people fly into Portland or Medford and fold preparation into the trip.
Is Ayeterra a psilocybin treatment center?
No, and neither is any licensed facilitator or service center in Oregon. Sessions happen at licensed psilocybin service centers, which are regulated venues, not clinics, and Ayeterra is a team of licensed facilitators who work at them. Nothing in the program is medical treatment.
Is it safe?
Psilocybin has low physiological toxicity and is not considered addictive. The meaningful risks are psychological: a hard experience, or destabilization for someone with certain histories. Screening exists to catch those histories, and the setting and your facilitator are there for the hard hours if they come. Oregon’s own program data from early 2025 show six reported reactions among 1,509 clients.
Will it show up on a drug test?
Standard 5- and 12-panel employment tests do not screen for psilocybin, and it clears the body quickly. Specialized tests can detect it if specifically ordered. If testing is part of your work life, raise it on the consultation.
What does it cost, and does insurance cover it?
Sessions with Ayeterra run from $75 for a low-dose group to about $2,100 to $2,300 all-in for a private one-on-one, with retreats from $3,000. Insurance does not cover psilocybin services in Oregon. Every price and what it includes is on the pricing page.
What if I am not sure this is right for me?
That is exactly what the consultation is for. It is free, there is no commitment, and you will get a straight answer, including “not yet” or “not this” if that is the honest one.
Ready to find out if this is a fit?
Everything starts with a conversation. Free, confidential, and no commitment: a chance to ask your questions and find out whether this is a fit, and when.
Book a free consultation Or call 503-713-5644 · Adults 21+Oregon Health Authority, Oregon Psilocybin Services. Access Psilocybin Services: preparation, administration, and integration sessions; eligibility criteria including lithium, active psychosis, and ideation of harm; 72-hour follow-up. oregon.gov/oha/ph/preventionwellness/pages/psilocybin-access-psilocybin-services.aspx
ORS 475A (Oregon Psilocybin Services Act, Measure 109, 2020), including ORS 475A.498, use allowed only at a service center under facilitator supervision, and ORS 475A.662, the 15 percent psilocybin tax. oregonlegislature.gov/bills_laws/ors/ors475A.html
OAR 333-333-5000 (Preparation Session Requirements), 333-333-5050 (Client Information Form), 333-333-5250 (Duration of Administration Session), 333-333-2015 (Allowable Species: Psilocybe cubensis only). Oregon Health Authority.
Oregon Health Authority, June 12, 2025. Oregon Psilocybin Services publishes interactive data dashboard: 1,509 clients served January to April 2025, six behavioral, medical, or post-session reactions reported. oregon.gov/oha/ERD/Pages/Oregon-Psilocybin-Services-publishes-interactive-data-dashboard.aspx
House Bill 4002 (Oregon, 2024), which recriminalized possession of small amounts of controlled substances outside licensed programs, amending Measure 110.
Davis AK, Barrett FS, May DG, et al. Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2021;78(5):481-489. Johns Hopkins.
Carhart-Harris R, Giribaldi B, Watts R, et al. Trial of Psilocybin versus Escitalopram for Depression. New England Journal of Medicine. 2021;384:1402-1411. Imperial College London.
Griffiths RR, Johnson MW, Carducci MA, et al. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer. Journal of Psychopharmacology. 2016;30(12):1181-1197. Ross S, et al., same journal and issue, NYU.
Ayeterra provides legal psilocybin facilitation in Oregon through facilitators licensed by the State of Oregon, under Oregon’s regulated psilocybin program. These services are not medical care, psychotherapy, or a substitute for diagnosis or treatment by a licensed medical or mental health professional, and anything we share is general education, not medical advice. Psilocybin is not right for everyone: participation is limited to adults 21 and over and involves screening. We do not promise specific outcomes, and experiences vary. If you are in crisis or thinking about harming yourself, call or text 988. Psilocybin services are not a substitute for crisis care or treatment.
Last updated September 15, 2026